Paraneoplastic Neurological Syndrome

"Early recognition of these syndromes is very important because they allow early diagnosis of the tumor and because they require vigorous treatment".

DR. JAIME GÁLLEGO
COORDINATOR. CENTRAL NERVOUS SYSTEM TUMORS AREA

What is paraneoplastic neurological syndrome?

Paraneoplastic neurological syndrome is a rare complication of cancer. In some patients with early cancer (lung, breast, lymphoma, etc.), the body itself detects the tumour cells and triggers an immune response in an attempt to eliminate them.

Sometimes, this immune response not only attacks the tumour cells but also, mistakenly, attacks the nervous system.

The Clínica Universidad de Navarra Cancer Centre has a Multidisciplinary Area for Central Nervous System Tumours with a wide range of human and technical resources.

This multidisciplinary approach allows us to offer patients the best possible treatment and, above all, to dedicate the necessary time to them. In this way we can offer personalised medicine.

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What are the symptoms of paraneoplastic neurological syndrome?

A wide variety of neurological symptoms and signs appear (memory and behavioural disorders, epileptic seizures, sensory or motor disorders, balance or visual disorders, etc.), which in turn are very disabling.

What illnesses does the patient have?

  • Memory disorders
  • Epileptic seizures
  • Sensory disorders

Do you have any of these symptoms?

If you suspect that you have any of the above symptoms,
you should consult a medical specialist for a diagnosis.

How is paraneoplastic neurological syndrome diagnosed?

To diagnose a paraneoplastic neurological syndrome, we must base our diagnosis on a set of data that, in addition to immunological markers, includes the clinical picture, the diagnosis of the tumour, the latency between neurological and oncological disease, neuroimaging, analysis of the cerebrospinal fluid by lumbar puncture and the response of the neurological syndrome to treatment of the tumour.

In patients already diagnosed with cancer and who present with a neurological condition, it is essential before making the diagnosis to rule out other much more frequent causes such as metastasis, drug effects, etc.

How is paraneoplastic neurological syndrome treated?

The main treatment for paraneoplastic syndromes is that of the tumor itself, associated with a treatment that modulates and blocks the abnormal immune response (corticoids, immunosuppressors, immunoglobulins, plasma exchange...).

Where do we treat it?

IN NAVARRA AND MADRID

Central Nervous System Tumors Area
of the Cancer Center Clínica Universidad de Navarra

In the Central Nervous System Tumors Area we offer maximum safety and efficiency in brain tumor surgery, being the first hospital with a high field magnetic resonance within the operating room.

We have a highly specialized team in the surgery of brain tumors, with more than 15 years of experience.

The individualized treatment of each case by an interdisciplinary team allows us to offer the best alternative to each patient.

Imagen de la fachada de consultas de la sede en Pamplona de la Clínica Universidad de Navarra

Why at the Clinica?

  • Integral evaluation of the patient.
  • Cutting edge technology.
  • Expert professionals who are a national reference.

Our team of experts in paraneoplastic neurological syndrome