Proton therapy for lymphomas
Treatment that preserves the heart, lungs and bone marrow in resistant and recurrent lymphomas
Proton therapy for lymphoma offers the best dosimetric optimisation as a salvage radiotherapy option for patients with chemotherapy-resistant lymphoma. For other types of lymphoma, the precision of the proton beam preserves critical healthy tissues — bone marrow, heart, breast, oesophagus and lungs — ensuring better local control of the disease and reducing side effects.
In selected cases of recurrent lymphoma, proton therapy is also an option for patients who have previously undergone external beam radiotherapy in the same area. The Advanced Therapies Unit at the Cancer Center Clinica Universidad de Navarra, with facilities in Madrid, specialises exclusively in cell therapies for lymphoma, facilitating their administration and enhancing the safety of these treatments.
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What are the causes?
The main risk factors include high alcohol and tobacco consumption, the combination of which increases the risk multiplicatively.
There are also precancerous lesions, such as caustic oesophagitis, Barrett's oesophagus, achalasia or Plummer-Vinson syndrome.
Barrett's oesophagus, associated with gastro-oesophageal reflux and chronic hiatus hernia, is the most important predisposing factor.
Other risk factors include a diet poor in fruit and vegetables, consumption of very hot foods, and foods containing nitrosamines (present in products such as beer, fish and processed meats).
Why at the Clínica Universidad de Navarra
The University of Navarra Clinic Cancer Centre has an Advanced Therapies Unit, which specialises exclusively in cell therapies for lymphoma, facilitating their administration and enhancing the safety of these treatments.

Reference Center
The Clínica Universidad de Navarra is an international reference center in the diagnosis and treatment of cancer, offering patients and their families access to an interdisciplinary approach to esophageal cancer.

A unique concept
First facility in Spain integrated in an Intrahospital Cancer Center, with all its assistance, academic and research support.

Advanced technology
As a highly complex center, we have the most advanced technology for the most accurate diagnosis in the shortest time possible.
The most precise radiation therapy for cancer
The Proton Therapy Unit’s technology allows the beam energy to be adjusted layer by layer, enabling the tumour to be targeted with maximum precision whilst ensuring the dose is precisely tailored, and allowing the exact position of the tumour to be verified daily before each session — a particularly important consideration in the case of lymphomas, where the proximity of critical organs such as the heart, lungs and bone marrow demands the utmost precision to preserve these tissues.