Reirradiation with proton therapy

Reirradiation with proton therapy is an advanced treatment especially valuable in situations where a patient needs to be irradiated a second time in the same area, something that is often risky or not possible with conventional radiation therapy due to the limited tolerance of healthy tissues to radiation.

Proton therapy has the unique advantage of releasing most of its energy at a specific point known as the "Bragg peak". This allows us to target a high dose of radiation to the tumor with exceptional precision, minimizing damage to surrounding tissues. This precision is crucial in re-irradiation, as the tissues around the tumor have already been exposed to radiation before and may be more susceptible to additional damage.

Because re-irradiation involves treating an area that has been previously irradiated, it is a delicate procedure that requires careful planning and thorough consideration of the risks and benefits. Proton therapy may be a preferable option in these cases, as its accuracy can reduce the risk of side effects and complications associated with additional radiation exposure.

The availability of fused multimodality imaging techniques, in particular biological imaging (PET), makes it possible to discriminate areas of necrosis, infection or active tumor that are frequent in these patients and to adapt the dose deposition avoiding areas of non-tumor.

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Why at the Cancer Center Clínica Universidad de Navarra?

With more than 8,600 patients treated per year, the Cancer Center Clínica Universidad de Navarra has accumulated almost 40 years of experience at the forefront of personalized medicine applied to cancer.

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treated with reirradiation, the main indications are brain, head and neck, and prostate tumors.

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Most experience in
in Spain

We are the first proton re-irradiation unit in Spain. Our professionals have the most experience in reirradiation treatment.

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Integrated in a
Cancer Center

First proton therapy facility in Spain integrated in an in-hospital Cancer Center, with all its assistance, academic and research support.

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Quality medical
quality medical care

We follow the European Professional Society Guidelines to offer our patients maximum safety and control.

How is the process of re-irradiation with proton therapy?


Multidisciplinary team assessment

which makes the decision in a shared manner. At this point, the team's expertise is crucial to carefully select patients who may benefit from reirradiation.


Correct assessment
of the patient

Clinical and radiobiological factors of the patient and his tumor are evaluated in order to correctly plan the ideal re-irradiation treatment.


Coordination of the
team of professionals

Throughout the process, medical oncologists, radiotherapists, radiophysicists, nurses specialized in patient care work together to offer personalized attention in this complex treatment.


Constant supervision
during the process

We carry out an exhaustive control by means of quality of life, toxicity and survival indicators to assess the patient's evolution.

Proton therapy Center in Madrid

The Proton Therapy Unit
of the Clínica Universidad de Navarra

The Proton Therapy Unit of the Clínica Universidad de Navarra in Madrid is the most advanced in Europe and the first in a Cancer Center, with all its assistance, academic and research support.

The Clinic's Proton Therapy Unit incorporates a Hitachi synchrotron, this technology is present in 32 clinical and academic centers, among which are international references in cancer treatment, such as the Mayo Clinic, MD Anderson, John's Hopkins, St. Jude's Children's Research Hospital or Hokkaido University Hospital.

More information about the Proton Therapy Unit

Why at the Clinica?

  • Expert professionals of international reference.
  • Greater accessibility for national and international patients.
  • Integrated within the Cancer Center Universidad de Navarra with the most advanced diagnostic technology, services and the latest advances in cancer treatment.